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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEPDC5
All Species:
13.64
Human Site:
Y663
Identified Species:
33.33
UniProt:
O75140
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75140
NP_001007189.1
1572
177910
Y663
A
E
L
L
E
L
A
Y
H
E
A
A
G
R
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852875
773
87442
Cat
Felis silvestris
Mouse
Mus musculus
P61460
1527
173129
Y621
A
E
L
L
E
L
A
Y
H
E
A
A
G
R
H
Rat
Rattus norvegicus
NP_001100699
1456
164725
M589
L
S
N
S
G
T
G
M
N
P
R
N
Q
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517877
828
93963
Chicken
Gallus gallus
XP_415249
1571
177723
Y663
A
E
L
L
E
L
A
Y
H
E
A
A
G
R
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691450
1590
178752
Y664
A
E
L
L
E
L
A
Y
H
E
A
T
G
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728620
1472
168864
T605
H
I
F
P
K
G
P
T
G
V
L
I
Q
Q
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794020
1608
181354
A674
P
Q
G
P
S
G
G
A
I
Q
T
H
H
R
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S9J6
2004
222187
A841
V
N
A
D
R
S
L
A
S
S
R
A
L
M
N
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
48
N.A.
91.7
87.4
N.A.
49.5
89.1
N.A.
75.5
N.A.
35.7
N.A.
N.A.
32.4
Protein Similarity:
100
N.A.
N.A.
48.6
N.A.
93.8
89.6
N.A.
50.9
94
N.A.
84.5
N.A.
53.7
N.A.
N.A.
48.6
P-Site Identity:
100
N.A.
N.A.
0
N.A.
100
0
N.A.
0
100
N.A.
80
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
0
N.A.
100
6.6
N.A.
0
100
N.A.
80
N.A.
20
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
0
10
0
0
0
40
20
0
0
40
40
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
40
0
0
40
0
0
0
0
40
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
10
20
20
0
10
0
0
0
40
0
0
% G
% His:
10
0
0
0
0
0
0
0
40
0
0
10
10
0
40
% H
% Ile:
0
10
0
0
0
0
0
0
10
0
0
10
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
20
% K
% Leu:
10
0
40
40
0
40
10
0
0
0
10
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
0
0
0
0
10
0
% M
% Asn:
0
10
10
0
0
0
0
0
10
0
0
10
0
10
20
% N
% Pro:
10
0
0
20
0
0
10
0
0
10
0
0
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
10
0
0
20
10
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
20
0
0
40
0
% R
% Ser:
0
10
0
10
10
10
0
0
10
10
0
0
0
10
0
% S
% Thr:
0
0
0
0
0
10
0
10
0
0
10
10
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
40
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _